How Africa Defeated COVID so Decisively Without Vaccines

Part of the African continent’s success is no doubt due to a fortunate accident of microbiology, infectious diseases, pharmacology and immunology. It so happens that two of the most effective treatments for COVID, ivermectin and hydroxychloroquine, are also routine prophylactic weekly medicines throughout equatorial Africa, because they happen to be known for a half-century as the most effective, applicable and safest anti-parasite medications. So the population, particularly through about 31 countries, the tropical middle rectangle roughly, of Africa already were well-equipped prior to COVID events launching in late 2019 to early 2020.

As fortune would have it, the unpatented and relatively inexpensive half-century old drug ivermectin, whose inventors won the Nobel Prize for Medicine in 2015, also has been the most effective medicine against COVID, [15] due in part to its specific effect against RNA transcriptase, as well as its blocking effect on all three parts of the trimeric spike protein, and other mechanisms.

Hydroxychloroquine is also used widely throughout at least equatorial regions of Africa as a prophylactic against parasites, but which fortunately has now been studied extensively and used successfully as both prevention and treatment of COVID disease, and as inhibitor of SARS-CoV-2 replication and activity. This is shown in over 380 studies conducted in 55 countries.

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